(Background and matrix will be ignored if not used by selected method.)

For consistency with the other methods, the Shannon entropy scores have been scaled to the range [0,1] and then subtracted from 1, so that higher scores indicate greater conservation.





Please cite the following paper if you use this tool:

Capra JA and Singh M. Predicting functionally important residues from sequence conservation. Bioinformatics, 23(15):1875-82, 2007.

Back to main page