bZIP Coiled-Coil Scoring Form

The bZIP-score program can be used to score possible bZIP pairings. It is based on the methods described in the following papers:

Jessica H. Fong, Amy E. Keating and Mona Singh, "Predicting specificity in bZIP coiled-coil protein interactions," Genome Biology, Volume 5, Issue 2. [Link to GenomeBiology]

Mona Singh and Peter S. Kim, "Towards predicting coiled-coil protein interactions," in Proceedings of the 5th Annual International Conference on Computational Molecular Biology, ACM 2001:279-286. [Link to ACM]

Please cite the above papers if you use this program.

This program has been designed for predicting bZIP coiled-coil interactions. While it may be used for general coiled coil partner prediction, we have not tested performance. To detect coiled-coil motifs in a sequence, please use the PairCoil or MultiCoil programs.

For questions about the computational method, send mail to us at: bzip at

Please enter two sequences, in their interaction alignment, and registers below in plain text format. For more information, please see the documentation of this page.

Interaction name (optional)

Sequence 1 (required):

Register (required)

Sequence 2 (required)

The results normally appear in 15-30 seconds.

[Program Help]

This server maintains confidentiality of the sequences submitted and does not store them. Bug fixes are tracked.

If results do not appear within 5 minutes after you submit your data, please notify us at:
For comments or suggestions please send mail to

visitors since January 20, 2004.